Interfacial catalysis of aldol reactions by prolinamide surfactants in reverse micelles.

Microheterogeneous surfactant-based systems as the media for enzymatic reactions

Surfactant aggregates (micelles) of various structure, size and shape are the systems with the media mostly close to those in natural (cell) systems. Hence, they are unique in their abilities for enzymologists whose task is to disclose the potentiality of enzymatic catalysis in vivo. By example of enzyme-containing systems of reverse micelles of surfactants in organic solvents, principal ways o...

Enantioselective direct aldol reactions catalyzed by L-prolinamide derivatives.

l-Prolinamides 2, prepared from l-proline and simple aliphatic and aromatic amines, have been found to be active catalysts for the direct aldol reaction of 4-nitrobenzaldehyde with neat acetone at room temperature. They give moderate enantioselectivities of up to 46% enantiomeric excess (ee). The enantioselectivity increases as the amide N-H becomes a better hydrogen bond donor. l-Prolinamides ...

Novel carbohydrate-derived prolinamide as a highly efficient, recoverable catalyst for direct aldol reactions in water

Hybrid Surfactants with N‐Heterocyclic Carbene Heads as a Multifunctional Platform for Interfacial Catalysis

Processing of substrates with different solvent compatibility is a persistent problem in homogeneous catalysis, in particular when one starting compound is water soluble and the other is not. A promising concept reported in the literature is micellar catalysis. However, the process of developing catalysts that are surfactants at the same time is still in its early stages. We report the synthesi...

Room temperature aldol reactions using magnetic Fe3O4@Fe(OH)3 composite microspheres in hydrogen bond catalysis.

Fe(3)O(4)@Fe(OH)(3) composite microspheres are highly active, environmentally friendly and easy to recycle catalysts for aldol reactions, which are catalyzed by a solid-liquid interfacial hydrogen bond catalyst at room temperature.